Neelroop Parikshak is developing methods for analysis and causative inference in systems neuroscience. John Paul and Neelroop first met at UCLA in spring of 2015 to discuss Neelroop's integrative systems neuroscience methods. Neel recently has published a number of reports outlining the novel approach.
This resource contains information regarding the network of colleagues in the integrative research program proposed in John Paul SanGiovanni's Stadtman Investigator Application. The team includes experts in biochemistry, bioinformatics, biophysics, biostatistics, clinical trials, developmental neurobiology, epidemiology, genomics, human nutrition, in vivo imaging, molecular biology, neonatology, pediatrics, psychiatry, structural chemistry, systems neuroscience, and vascular biology.
Overview
The cardinal goal of Dr. SanGiovanni's project is to determine whether lipid-sensing complexes interacting with molecular targets in dopamine-based signaling cascades may be appreciably modulated by exposure to essential, brain-resident nutrients or their metabolites – and, if so, whether such effects have value for explaining resilience or informing development of preventive or therapeutic interventions during periods of vulnerability.
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