Overview

The cardinal goal of Dr. SanGiovanni's project is to determine whether lipid-sensing complexes interacting with molecular targets in dopamine-based signaling cascades may be appreciably modulated by exposure to essential, brain-resident nutrients or their metabolites – and, if so, whether such effects have value for explaining resilience or informing development of preventive or therapeutic interventions during periods of vulnerability.

Wednesday, September 30, 2015

Biostatistics and Inference on High-Dimensional Omics Data -- Brooke Fridley (U. Kansas)

Brooke Fridley has extensive expertise in high-dimensional statistical genetics and is devoting her efforts as Director of The Biostatistics and Informatics Shared Resource at The University of Kansas Cancer Center to development of methods for data integration, including Bayesian methods, molecular clustering and gene set analysis approaches.  Pharmacogenomics is a topical focal point of her recent work.   Brooke has recently authored a number of important methodologic reports on (a few for gene set analysis are referenced below) and published pertinent software packages.  Methods papers outlining Brooke's approach may be accessed at the links below:


The current collaboration is the first for John Paul and Brooke.





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